what could cause a woman to lose an ovary
Principal Ovarian Insufficiency
Besides called: Ovarian insufficiency, POF, POI, Premature ovarian failure
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Summary
What is chief ovarian insufficiency (POI)?
Primary ovarian insufficiency (POI), likewise known as premature ovarian failure, happens when a adult female's ovaries terminate working normally earlier she is 40.
Many women naturally experience reduced fertility when they are about twoscore years old. They may beginning getting irregular menstrual periods as they transition to menopause. For women with POI, irregular periods and reduced fertility starting time before the age of xl. Sometimes it can start as early as the teenage years.
POI is dissimilar from premature menopause. With premature menopause, your periods stop before age 40. You lot tin can no longer get significant. The cause can be natural or it tin be a affliction, surgery, chemotherapy, or radiation. With POI, some women still take occasional periods. They may fifty-fifty get meaning. In most cases of POI, the crusade is unknown.
What causes primary ovarian insufficiency (POI)?
In almost 90% of cases, the exact cause of POI is unknown.
Research shows that POI is related to problems with the follicles. Follicles are minor sacs in your ovaries. Your eggs grow and mature inside them. One type of follicle problem is that you lot run out of working follicles before than normal. Another is that the follicles are not working properly. In most cases, the cause of the follicle problem is unknown. Merely sometimes the cause may exist:
- Genetic disorders such as Fragile X syndrome and Turner syndrome
- A low number of follicles
- Autoimmune diseases, including thyroiditis and Addison disease
- Chemotherapy or radiation therapy
- Metabolic disorders
- Toxins, such as cigarette fume, chemicals, and pesticides
Who is at take a chance for chief ovarian insufficiency (POI)?
Certain factors tin can enhance a woman'south take a chance of POI:
- Family history. Women who have a female parent or sister with POI are more than probable to take information technology.
- Genes. Some changes to genes and genetic weather put women at higher risk for POI. For case, women Delicate X syndrome or Turner syndrome are at higher risk.
- Certain diseases, such as autoimmune diseases and viral infections
- Cancer treatments, such as chemotherapy and radiation therapy
- Age. Younger women can get POI, but information technology becomes more than mutual between the ages of 35-twoscore.
What are the symptoms of primary ovarian insufficiency (POI)?
The get-go sign of POI is commonly irregular or missed periods. Later symptoms may be similar to those of natural menopause:
- Hot flashes
- Nighttime sweats
- Irritability
- Poor concentration
- Decreased sexual practice drive
- Hurting during sex activity
- Vaginal dryness
For many women with POI, trouble getting pregnant or infertility is the reason they become to their health care provider.
What other bug can primary ovarian insufficiency (POI) cause?
Since POI causes you to have lower levels of sure hormones, you are at greater run a risk for other wellness conditions, including:
- Anxiety and depression. Hormonal changes acquired by POI can contribute to anxiety or lead to depression.
- Dry eye syndrome and eye surface disease. Some women with POI accept one of these eye atmospheric condition. Both tin can crusade discomfort and may pb to blurred vision. If not treated, these conditions tin crusade permanent centre damage.
- Heart illness. Lower levels of estrogen can affect the muscles lining the arteries and can increase the buildup of cholesterol in the arteries. These factors increment your risk of atherosclerosis (hardening of the arteries).
- Infertility.
- Low thyroid function. This problem also is called hypothyroidism. The thyroid is a gland that makes hormones that control your trunk'due south metabolism and energy level. Low levels thyroid hormones tin touch your metabolism and tin cause very low energy, mental sluggishness, and other symptoms.
- Osteoporosis. The hormone estrogen helps keep bones strong. Without enough estrogen, women with POI often develop osteoporosis. It is a bone disease that causes weak, breakable bones that are more likely to break.
How is master ovarian insufficiency (POI) diagnosed?
To diagnose POI, your health care provider may exercise:
- A medical history, including asking whether you lot accept relatives with POI
- A pregnancy test, to brand certain that yous are not pregnant
- A physical exam, to look for signs of other disorders which could be causing your symptoms
- Blood tests, to check for certain hormone levels. You may also have a blood test to practice a chromosome assay. A chromosome is the part of a cell that contains genetic information.
- A pelvic ultrasound, to run into whether or not the ovaries are enlarged or have multiple follicles
How is chief ovarian insufficiency (POI) treated?
Currently, at that place is no proven treatment to restore normal role to a woman'south ovaries. But at that place are treatments for some of the symptoms of POI. There are as well ways to lower your health risks and treat the conditions that POI tin crusade:
- Hormone replacement therapy (HRT). HRT is the most common handling. It gives your body the estrogen and other hormones that your ovaries are non making. HRT improves sexual health and decreases the risks for heart affliction and osteoporosis. You usually have information technology until about age 50; that's near the age when menopause commonly begins.
- Calcium and vitamin D supplements. Because women with POI are at college gamble for osteoporosis, you lot should take calcium and vitamin D every day.
- In vitro fertilization (IVF). If you accept POI and yous wish to become significant, you may consider trying IVF.
- Regular physical action and a healthy trunk weight. Getting regular exercise and decision-making your weight can lower your risk for osteoporosis and heart disease.
- Treatments for associated conditions. If y'all have a condition that is related to POI, it is important to treat that besides. Treatments may involve medicines and hormones.
NIH: National Constitute of Child Health and Human being Development
- What Are the Treatments for Primary Ovarian Insufficiency (POI)? (Eunice Kennedy Shriver National Found of Child Wellness and Homo Evolution) As well in Spanish
Source: https://medlineplus.gov/primaryovarianinsufficiency.html
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